In the others, Kenya's Asbel Kiprop seeks a fourth straight 1,500-metre gold; Ethiopian Almaz Ayana to complete a rare women's distance running double in the 5,000m, and Caster Semenya is the top favourite for a second 800m title a year after Olympic gold.
Bolt refused to be taken off the track in a wheelchair or stretcher, but it was still a hugely disappointing way for him to end a glittering career that has seen him dominate sprinting for over a decade. Bolt was the final leg for his team on this race.
"Usain Bolt's name will always live on", he said.
"It gets to the point where it kind of fuels you", he said. "We will never get this feeling again". "I gave it my all and I really wanted Usain to leave golden, or even if it was just a medal".
"I think it was the elements (that caused the injury)", he said. Tactically, I was trying to cover every move.
They say anything can happen in the 4x100m relay but truth is no one expected this: Bolt looked certain to add a medal of some colour to his already 11 World Championship gold medals won over the last decade, two silvers, and not forgetting the bronze medal won in the 100m final last weekend. We were hanging around inside the stadium for too long with our clothes off and i think that's where Usain Bolt's injury came from. "I lost all my sweat and body heat", Gatlin said.
"The 10,000m took a lot more out of me than I had realized", he told BBC Sport.
Sir Mo Farah claims silver medal in 5000m at World Championships
Quite simply, Farah will go down in history as Britain's best-ever athlete and one of the greatest the world has ever witnessed. America's Paul Kipkemoi Chelimo finished in 13 mins 33.20 secs to take bronze.
When asked if he thought that contributed to Bolt's injury, the 35-year-old said: "I believe so". At these championships, he had to settle for a bronze medal in the 100-meter race.
The four-time Olympic champion failed to mount a third defence of the 5000m as Ethiopia's Muktar Edris claimed gold in London on Saturday.
Jamaica were afforded a rousing welcome from the crowd, a relaxed-looking Bolt applauding the stands, with pictures of him constantly shown on the stadium's big screens.
In the day's only preliminaries, the United States dominated the women's and men's 4x400m heats into the finals which conclude the championships as part of 11 medal events Sunday.
But while that result left a spent Farah flat on the track with his head in his hands, the emotion amongst Britain's young female sprinters as they danced with delight on their lap of honour could not have been more different.
He later rose again and limped away without speaking to reporters.
"For me it's hard to be sad because the energy I'm getting from the crowd is brilliant, I'm just happy".