What are the premutations for tonight's game we hear you ask.Here's a quick reference quide of what each team needs to do to secure a play-off place with automatic qualification still a slim possibility should Gerogia surprise Serbia in Belgrade.with a win.
There is still a chance for either side to top Group D, but that will depend on group leaders Serbia's result against Georgia.
This would depend on who won their match tonight, as both Wales and the Republic could still come top of their group.
But what results do we need to make it to Russian Federation? 'It will very be similar to the game in Dublin where two sets of committed players were locking horns.
A loss means Wales will finish third. There may be no difference at all in the way Ramsey plays for his club, but I for one think that Wales i9s important to him and does affect his form, attitude etc.
Winning would guarantee second place and a play-off spot.
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Republic of Ireland manager Martin O'Neill has acknowledged that Seamus Coleman will be in the minds of the players in Cardfiff this evening.
The 28-year-old said: "It's a sticky one because in the press, you're talking about the Wales game and everybody expects us to walk over Moldova".
Before the defeat, Coleman called the current Wales squad a "golden generation", telling the Daily Telegraph: "I fought against it when they were labelled the "golden bunch" before we qualified for the Euros but now they've earned it". Yet it was clear that they would have to attack more purposefully after the interval and it was a beautifully taken goal that changed the complexion of the match.
"The job was to get the three points [against Moldova] no matter what and now we are fully focused and hopefully there will be a big crowd from Ireland". Victory there will send the nation to its first World Cup since 2002.
Chris Coleman, who saw his Wales side win 1-0 in Georgia three days ago, made just one personnel adjustment, with Hal Robson-Kanu being preferred to Sam Vokes up front.
"I just feel it is a wonderful night for soccer and it's a form of vindication for Martin O'Neill in particular".