On Monday, US President Donald Trump sent his first National Security Strategy report to lawmakers.
Tensions have continued to rise between North Korea, its regional rivals and the United States.
North Korea is believed to have started its chemical and biological weapons program in the early 1960s and began possibly weaponizing biological agents in the 1980s, according to the report. However, North Korea has set to ideal its re-entry technology.
"North Korea-a country that starves its own people-has spent hundreds of millions of dollars on nuclear, chemical, and biological weapons that could threaten our homeland", the document said.
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In response, North Korea said it would "take revenge" on the USA for saying it is developing biological weapons. When an intercontinental ballistic missile reenters the earth's atmosphere, it could reach about 7000 degrees of heat.
The Director of Press of the Institute for American Studies of North Korea Ministry of Foreign Affairs said in a statement that such accusation is another example of the U.S. habit to pander fiction as "truth", Xinhua news agency reported.
Secretary of State Rex Tillerson also announced a new worldwide group Tuesday to increase the pressure on North Korea for a diplomatic solution to the global crisis over the regime's growing nuclear and ballistic missile programs.
North Korea has used chemical agents in the past to conduct attacks and assassinations, such as the February 2016 assassination of Kim Jong Un's half brother Kim Jong Nam using a VX agent at Malaysia's Kuala Lumpur International Airport.