The craft took an image at a record-breaking 6.12 billion kilometres, or 40.9 astronomical units, away from Earth.
The probe continues to cover around 1.1 million kilometres or 700,000 miles of deep space every day, and is only the fifth man-made object in history - after Pioneer 10, Pioneer 11, Voyager 2, and Voyager 1 - to be on course to fly beyond the reaches of our Solar System.
These December 2017 false-color images of Kuiper belt objects were taken from the farthest distance from Earth of any spacecraft ever.
Most of the time, New Horizons is sleeping - hibernating, to save energy. They are also the closest-ever images of Kuiper Belt objects.
Those snapshots of the December 2012 KBO 2012 HZ84 and 2012 HE85 are so far the furthest ever captured by a spacecraft, and the closest to any body of Kuiper, the agency stressed in a statement.
With its Long Range Reconnaissance Imager (LORRI), New Horizons has observed several Kuiper Belt objects (KBOs) and dwarf planets at unique phase angles, as well as Centaurs at extremely high phase angles to search for forward-scattering rings or dust.
"New Horizons has always been a mission of firsts -- first to explore Pluto, first to explore the Kuiper Belt, fastest spacecraft ever launched", Alan Stern, the mission's principal investigator, said in the NASA statement.
Trump asks Pentagon to plan military parade
Adam Smith of Washington said in a statement . " It was one of the greatest parades I've ever seen ", Trump had told the reporters.
The Pale Blue Dot was the final picture beamed back to Earth by Voyager 1, now the most distant thing made by humans and the first craft to cross into interstellar space.
That picture was part of a composite of 60 images looking back at the solar system, on February 14, 1990, when Voyager was 3.75 billion miles from Earth.
NASA says its New Horizons spacecraft made an image using its telescopic camera to make an image 3.79 billion miles from Earth, which makes it the farthest one ever made from our planet. During its travels, New Horizons alternates between periods of activity and dormancy to conserve fuel. The spacecraft was at a distance of 6.12 billion kilometers (3.79 billion miles) when it captured the images.
It wasn't until this past December when Voyager 1's record was finally broken.
The Wishing Well star cluster. That was followed up with the shots of the Kuiper Belt two hours later. (Dwarf planet Pluto is a part of the belt, but it was not recognized as such until the discovery of other Kuiper objects in the early 2000s.) Pluto was estimated in 2015 to be the largest object in the belt, though there are other dwarf planets of note, such as Eris, Haumea and Makemake.
New Horizons was launched on January 19, 2006.