But it was not to be and the defeat meant a club record of seven home Premier League games without victory was equaled.
"We knew the strengths of Southampton and how they want to play football, so we wanted to defend and change the game to counter", Klopp told Sky Sports.
The African forward started the weekend one goal adrift of the Premier League's leading goal-scorer Harry Kane before the England worldwide netted the victor in the north London derby.
Liverpool have been particularly strong on their travels this season and have scored a league-high 34 goals.
United States strikes on Syria kill 100 regime troops
The US has backed the Syrian Democratic Forces in their fight against the Islamic State group in northern and eastern Syria. The United States maintains about 2,000 troop in Syria, mostly working with the estimated 50,000 Syrian Democratic Forces.
"The second half was really bad", he said.
LIVERPOOL, ENGLAND - JANUARY 27: Virgil van Dijk of Liverpool reacts during The Emirates FA Cup Fourth Round match between Liverpool and West Bromwich Albion at Anfield on January 27, 2018 in Liverpool, England.
Firmino struck early after Southampton centre-back Wesley Hoedt's mistake, as the Dutchman horribly misjudged a Liverpool ball forward and gifted possession to the last player on the pitch that the Saints should allow to have the ball, Salah.
The Saints haven't beaten a top-six side in the league now for over 18 months and the Reds ran ragged last time out and have a lot of quality in their ranks. "We understand the emotions of the fans but we have to keep this going". "But I think we deserved the three points, clean sheets and no injuries, it was flawless". We had a little chat before the game, asking him what he thought.