Firmino and Salah in particular had been in fine form leading into the match, with the Egyptian scoring in each of his last four appearances across all competitions before the trip to Porto.
"We will make them suffer", the 26-year-old said through a translator. "Not conceding goals, we are always closer to winning the game, no doubt".
Jurgen Klopp's side topped Group E, averaging nearly 4 goals a game while they did it, and will arrive in Portugal in confident mood after taking 7 points from the last 9 in domestic football.
"They had their chances in these situations, they had possession and played good football", he continued.
The Saints came into this clash unbeaten in six games and looking for their first back-to-back league wins since April past year, but were undone by the quality of Liverpool's front-line and now remain winless at St Mary's since November 26. If we are in the final then I'll say we will try to win it but that is too far off.
Ousmane Dembele Is Unhappy At The Club
"I think there's a real maturity about Mo Salah now", Lampard told BT Sport.
"I'll ask Rafa (Benitez) but that would surprise me because it makes no sense".
Mestre admitted the departure of Neymar contributed to a "little earthquake" in the club but they are now back on the right tracks. I hate to talk about the round after the actual round.
"Each team has their way of playing and I am still learning how to play here, every day doing the best I possibly can".
Their seven-game streak without a home league win is a joint club record and sees them remain in the relegation zone, one point away from 17th-placed Huddersfield.
Kim Jong Un Impersonator Shows Up At Olympics, Taken Away By Police
Numerous cheerleaders giggled nervously and waved back, but when the fake Kim broke into an impromptu jig all hell broke loose. In North Korea, anyone impersonating of a member of the ruling Kim family would be considered blasphemous.