They also have higher rates of clotting in the lungs and a narrowing of peripheral arteries.
"From this study, we believe that varicose veins are not merely a cosmetic or symptomatic concern", Chen said. Have you got varicose veins?
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While many people feel self-conscious about their varicose veins, enlarged and twisted veins that form just under the skin, the study suggests they could also put your health at serious risk. While commonly affecting people due to their unsightly appearance, China Medical University's study has linked the condition to deep-vein thrombosis. The HR for the association of varicose veins with PE was 1.73 (95% CI 1.54-1.94) compared with the control group. However, the association to these conditions was "less clear due to the potential for confounding", by factors such as smoking history or obesity - information not available in the claims data.
Every year around 25,000 people in the United Kingdom bite the dust from a blood clot in a vein, and the condition is additionally the third driving reason for heart assaults and strokes. Piazza, who was not involved in the research, explained that the researchers "undertook several additional statistical techniques" to weaken possible confounding factors that might bias the results, and "these steps help to build a case for the study observations being robust".
Inflammation has become "increasingly recognized as a key player in the development of vascular disease, including deep venous thrombosis, pulmonary embolism, stroke and heart attack", Piazza said. Furthermore, endovenous ablation provides quick recovery which in turn is expected to create demand for varicose vein treatment. The mean age at diagnosis in the varicose vein group was 54.5 years, and 69.3% were women. Researchers tracked more than 200,000 patients and say more study is needed.