A bomb blast targeting a security chief in Egypt's coastal city of Alexandria killed a policeman and wounded four others on Saturday - just two days before presidental elections.
The ministry said the bombing had targeted the convoy of Alexandria's security chief, General Mostafa al-Nemr.
A number of civil protection officers, firefighters, police and emergency services have reportedly arrived at the scene and formed a perimeter around blast site.
The bomb was placed under a parked vehicle and exploded as Mostafa El-Nemr's convoy was passing, killing the two officers, ages 45 and 19, and injuring about five other policemen. It was reported that the public prosecutor has ordered an investigation.
Egyptian president Abdel Fattah El Sisi has made security one of the main planks of his re-election campaign.
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Witnesses said security and military units had cordoned off the area of the attack, which left several burnt-out cars.
No group has claimed responsibility for the attack. But the Islamic State militant group has been calling for attacks to disrupt the election, which runs for 3 days from Monday.
IS claimed the 2015 bombing of a Russian airliner carrying tourists from the South Sinai resort of Sharm el-Sheikh, which killed all 224 people on board.
It has also killed scores of members of Egypt's minority Coptic Christian community in church bombings and shootings.