Iranian President Hassan Rouhani has said the world will "not accept" U.S. unilateralism just hours after Washington laid out a series of tough demands to be included in a potential new nuclear treaty with Iran.
USA sanctions lifted after the 2015 deal will be re-imposed, Mr Pompeo said, and those and new measures will together constitute "unprecedented financial pressure on the Iranian regime".
The demands include giving the International Atomic Energy Agency a full account of the country's former nuclear military programme, withdrawing its forces from Syria and ending what Pompeo described as Iran's "threatening behaviour" towards its neighbours.
After the 1979 Iranian revolution, USA oil companies lost a major source of profits, and according to Izade, "the US wants to restore economic, political and military control over Iran as it tried to do in Iraq".
"This list may seem long to some, but it is simply a reflection of the massive scope of Iranian malign behavior", Pompeo said.
US President Donald Trump sparked an global outcry earlier this month when he announced his country would pull out of the landmark accord struck in July 2015 between Tehran and major world powers.
"From here I will actually travel to Washington to have a meeting with Secretary Pompeo, and take advantage of that meeting to talk about this", Maas said in response to a question from a journalist about the Iran deal.
Izadi, an expert on the JCPOA and advisor to Iran's Foreign Ministry, said Iran may also step up the training of nuclear scientists.
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"Reported use of excessive force and live ammunition is inexcusable", the prime minister's statement continued. The Palestinians held a one-day general strike and called for three days of mourning for the victims.
Formally known as the Joint Comprehensive Plan of Action (JCPOA), the so-called Iran nuclear deal - an Obama-era agreement between Iran and the United States, the United Kingdom, Germany, France, Russia, China, and the European Union - was established to reward Iran for curbing its nuclear program.
Iran foe Israel's Prime Minister Benjamin Netanyahu hailed Pompeo's speech, and urged the rest of the world to follow suit. "At the end of the day, the Iranian people will get to make a choice about their leadership".
Political analyst Jamal Abdi said the U.S. knew that Iran could never agree with such demands. "Who are you to decide for the world?" he told the Iranian media. "These will be the strongest sanctions in history by the time we are complete".
Media captionIran nuclear deal: Trump announces United States pull-out Why is Iran seen as a regional threat? His book The Iran Agenda Today: the Real Story of U.S. Policy and the Middle East Crisis (Routledge Books) will be published this Fall.
"We will continue to work with our allies to counter the regime's destabilizing activities in the region, block their financing of terror, and address Iran's proliferation of missiles and other advanced weapons that threaten peace and stability", Pompeo said.
The Iranians are unlikely to go along with any of Pompeo's demands, including a stop to uranium enrichment and ballistic missile tests, and allowing worldwide inspectors access to all sites.
European nations, as well as Russian Federation and China, are vowing to stand by the deal - formally known as the Joint Comprehensive Plan of Action - that Iran reached with six world powers and are trying to insulate their companies from the promised sanctions even though that's an uphill effort. The secretary appealed to Iran's supreme leader, Ayatollah Ali Khamenei, a hard-liner, to "summon the courage to do something historically beneficial" for his people.
"We will apply unprecedented financial pressure on the Iranian regime", Pompeo said, adding that the sanctions will be "painful" and "the strongest in history". "If Iran wanted to pursue a peaceful nuclear program they wouldn't need to hide their nuclear archive".