The openers shared a 160-run partnership and smashed 13 fours and 10 sixes between them.Despite losing a cluster of wickets towards the end, India accumulated 208 runs for five in their stipulated 20 overs, setting Ireland a tough target of 209 runs to win.
India left for Dublin on Tuesday after having a practice session in London on Monday.
Skipper Virat Kohli and the in-form KL Rahul batted together in adjacent nets against spin and pace respectively.
While the opening slot is set for Shikhar Dhawan and Rohit Sharma, the likes of KL Rahul, Suresh Raina, Manish Pandey, and Dinesh Karthik will be vying for the middle-order spots in the absence of Ajinkya Rahane and injured Kedar Jadhav.
While Raina also provides a sixth bowling option combined with his batting, India would also not want to drop Karthik, who is in sizzling form since March. It could mean that Pandey eventually warms the bench, despite scoring 255 runs in 8 T20Is this year against South Africa, Sri Lanka and Bangladesh at an average of 85.
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It's a rare occasion when the former Indian skipper had to sit out despite being in the squad.
Rohit, Dhoni and Karthik were part of that squad, albeit Karthik was picked ahead of Dhoni in the playing eleven for that one-off game.
India passed 200 in back-to-back T20s for the first time in posting 213 for four, before dismissing the Irish for a paltry 70 inside 12.3 overs. Although their margin of defeat in the 1st T20I was 76 runs, the home side were quite impressive.
With Pandya as the third seaming option, it will also be interesting to see whether medium pacer Siddharth Kaul makes his India debut after an impressive stint in the Indian Premier League (IPL).
India Vs Ireland today's match starts at 8:30 pm IST and will be shown on Sony Six.
Ireland: Gary Wilson (c), Andrew Balbirnie, Peter Chase, George Dockrell, Joshua Little, Andy McBrine, Kevin O Brien, William Porterfield, Stuart Poynter, Boyd Rankin, James Shannon, Simi Singh, Paul Stirling, Stuart Thompson.